Crystal Engineering of Nutraceutical Phytosterols

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A cocrystal screening conducted with a solid solution of three phytosterols (β-sitosterol, campesterol and stigmasterol) and a set of coformers with strong hydrogen bond donors reveals that multicomponent solid-solutions are preferentially formed instead of pure cocrystals and much enriched with β-sitosterol with respect to stigmasterol, a natural product with cytotoxicity concerns.

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