CIR-P56. A highly bioavailable Pterostilbene

CIR-P56 contains a unique patented combination of pterostilbene and picolinic acid, making it more efficient than any form of pterostilbene in the market!

What is Pterostilbene?

Pterostilbene is a stilbenoid found in many natural sources, predominantly in blueberries. It is chemically related to the more well-known resveratrol, but with higher oral bioavailability.

As an emerging antioxidant that is attracting a lot of attention since evidences suggest that pterostilbene may have preventive and therapeutic properties in a long list of human diseases which include neurological, cardiovascular, metabolic, and hematologic disorders. In addition, it has been reported that it can be a potent anticancer agent.

Helps slow the aging process

Helps fight and prevent cancer

Boosts brain health and prevents Alzheimer’s

Reduces your risk for heart disease

Helps regulate blood sugar and manage diabetes

What problems can we find?

Standard pterostilbene has limited oral bioavailability (only 5-16% of the total intake) and very poor solubility in water. It is also easily oxidized by several enzymes. 

The poor solubility of this compound as well as its sensitivity to external agents such as air, light, and oxidative enzymes can establish serious problems for its bioavailability and, therefore prevent pterostilbene from achieving its desirable activity. 

CIR-P56. A highly bioavailable Pterostilbene

Through an extensive study, CIRCE has discovered a new solid form of pterostilbene. CIR-P56, by combining pterostilbene with picolinic acid on a molecular level, improves its bioavailability 10 times up to >99%, making it much more efficient than other existing alternatives. 

It conveniently provides consumers with additional health benefits, as picolinic acid is well known for improving the absorption of Zinc, Chrome and other key minerals. 

Bioavailability test of pterostilbene vs. CIR-P56

You can find more information about our research at https://pubs.acs.org/doi/10.1021/acs.cgd.0c01716