Ubiquinol is vital for providing energy to cells, helping organs perform at their best, protecting cells and blood from oxidation. As the body ages, the natural Ubiquinol levels slowly decline. These important biological roles have motivated the use of Ubiquinol as dietary supplements for improving body protection against aging by oxidative stress with a particular focus on heart and neurodegenerative diseases.
However, the oral bioavailability of the highly lipophilic coenzyme Q10 is very low with an extremely poor aqueous solubility (0.7 ng/ml). Moreover, it shows a chemical instability upon exposure to air, light and high temperature, which makes it difficult to prepare efficient pharmaceutical formulations.